Whole genome sequencing can identify and isolate genetic variations. WGS reconstructs and reads through a patient’s genes to assist the confirmation, prediction, or explanation of a patient’s risk for disease, susceptibility to toxins, and responsiveness to treatment. In a research setting, WGS can help answer complex questions quickly and accurately.
By mapping a patient, animal, or plant’s unique chemical code, whole genome sequencing provides an overall view of their complete set of genes. Instead of narrowing in on a specific section of a DNA sequence, whole genome sequencing analyzes larger data sets to detect single nucleotide variants, insertions, deletions, copy number changes, and large structural variants.
With a wider scope of reference material, whole genome sequencing helps genome experts to develop an understanding of how certain stretches of DNA function and how they’re related. This greater comprehension of how genomes work as a whole is being applied in clinical settings, and to advance research on hundreds of species.