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Customer Publications

We love seeing our clients succeed! Take a look at some ground-breaking customer publications below.

Phylogenetic analysis of Michigan's freshwater sponges (Porifera, Spongillidae) using extended COI mtDNA sequences

Whole-Genome Sequencing

Impact of African-enriched GATM regulatory variants on creatinine-derived estimated glomerular filtration rate
iSCORE-PD: an isogenic stem cell collection to research Parkinson's Disease
An integrated germline and somatic genomic model for coronary artery disease

Whole-Exome Sequencing

Impact of African-enriched GATM regulatory variants on creatinine-derived estimated glomerular filtration rate
iSCORE-PD: an isogenic stem cell collection to research Parkinson's Disease
An integrated germline and somatic genomic model for coronary artery disease

Reconstructing the lineage histories and differentiation trajectories of individual cancer cells in myeloproliferative neoplasms

Sanger Sequencing

Electrostatic Contribution of K339 to the Flavin Reduction of Pseudomonas aeruginosa PAO1 d-2-Hydroxyglutarate Dehydrogenase
Mesenchymal drift in ciliopathy iPSC-derived RPE reveals a convergent pathogenic cell state
Dopamine D2 receptors bypass canonical signaling to directly tune NMDA receptor function and aversive learning

Single-Cell Sequencing

A self-amplifying nerve-fibroblast circuit drives colorectal cancer progression
Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits
Monocytic niches escape T cell surveillance and promote Mycobacterium tuberculosis persistence in lymph nodes

High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate the progression of pancreatic cancer

Transcriptomics

Transcriptomic reprogramming underlies perfluorobutanoic acid (PFBA)-induced hormesis in the fall armyworm, Spodoptera frugiperda
Total tocopherol levels in maize grain depend on chlorophyll biosynthesis within the embryo
Ex vivo expansion and hydrogel-mediated in vivo delivery of tissue-resident memory T cells for immunotherapy

Proteomics

Transthyretin V122I variant and protein affect cardiac severity and mortality in sickle cell disease
BCMA-directed mRNA CAR-T cell therapy for myasthenia gravis: exploratory biomarker analysis of a placebo-controlled phase 2b trial
Circulatory prostate cancer proteome landscapes and prognostic biomarkers in metastatic castrate resistant prostate cancer

Episymbiotic Saccharibacteria suppresses gingival inflammation and bone loss in mice through host bacterial modulation

Oncology

Circulatory prostate cancer proteome landscapes and prognostic biomarkers in metastatic castrate resistant prostate cancer
Ex vivo expansion and hydrogel-mediated in vivo delivery of tissue-resident memory T cells for immunotherapy
A Phase II Open-Label, Randomized Clinical Trial of Atezolizumab with or without Human Recombinant IL-7 (CYT107) in Advanced Urothelial Cancer

Inherited Disease Research

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits
Single-cell spatial transcriptomics unravels the cellular landscape of abdominal aortic aneurysm
Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of VWD and bleeding

Kinetic variation in grass phosphoenolpyruvate carboxylases provides opportunity to enhance C4 photosynthetic efficiency

Infectious Disease Research

A human YEATS4 variant confers resistance to TST and IGRA conversion despite Mycobacterium tuberculosis exposure
Molecular Characterization of Plasmodium Species to Strengthen Malaria Surveillance in Migrant Populations in Honduras
Early and opposing neutrophil and CD4 T cell responses shape pulmonary tuberculosis pathology

Reproductive Health Research

The Impact Of Genetic Mutations In 5α-Reductase Enzyme And INSL3 Hormone On The Development Of Hypospadi-as And Cryptorchidism
Identification of TSSK1 and TSSK2 as Novel Targets for Male Contraception
TSSK3, a novel target for male contraception, is required for spermiogenesis

Distribution and phylogenetic diversity of Anopheles species in malaria endemic areas of Honduras in an elimination setting

Metagenomics

Effects of a three-year maize-soybean rotation on soil bacterial diversity and fumonisin-producing Fusarium spp. inoculum potential
Dietary shifts illuminate host–microbiome-diet interplay in black soldier fly larvae
Vaginal microbiota impacts of a Lactobacillus crispatus live biotherapeutic and predictors of colonization in randomized controlled trial