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Macrogen Corp Announced as precision FDA Participating Provider

Macrogen Corp., one of the leading providers of next-generation sequencing services, has been announced as a participating provider in precisionFDA. The precisionFDA web platform is part of President Obama’s vision with his Precision Medical Initiative announced last year. The administration’s goal is to move away from a “one-size-fits-all” approach to medicine and move towards a […]

The Top Five Genome Conferences In The World

The emergence and growth of whole genome sequencing technologies, and the resulting immense database generated, requires that scientists and medical professionals learn more about the powerful tools available to them. These tools give scientists the ability to interpret and apply the information and are becoming increasingly available. Genomic technologies have bolstered the power of personalized […]

Managing High-Throughput DNA Sequencing Data

Introduction The newest sequencing technologies are providing new insights into disease etiology, individual susceptibilities, keys to drug discovery, and more. However, there are many questions and challenges regarding how to understand the meaning and applicability of the newfound wealth of data. As new data is generated at record rates, scientists are working diligently on the […]

Macrogen Deploys Advanced Data Processors for Faster Analysis of Large-Scale Genomic and Sequencing Data

Macrogen recently partnered with Edico Genome to reinforce its Bio-IT infrastructure with new DRAGEN processors. By deploying several DRAGEN Bio-IT Processors, which are designed and manufactured by Edico Genome, Macrogen will be able to provide faster processing and analysis of high-throughput NGS data. Accurate DNA sequencing and genomic analysis is reliant on advanced technology. To […]

How the Genome Asia 100K Initiative is Impacting Disease Research

The Genome Asia 100K Initiative announcement made big waves earlier this year as it is the first significant pan-Asian endeavor with the goal of creating a comprehensive genomic database. The initiative is similar to the 100K Genome Project in the United Kingdom and the US Precision Medicine Initiative. The Genome Asia 100K initiative is led […]

Discovering Drug Resistance Using DNA Sequencing

What is Drug Resistance? The World Health Organization (WHO) defines drug resistance (also called antimicrobial resistance) as the change that occurs in microorganisms that renders medications ineffective. There are other types of drug resistance, such as cancer cell resistance to chemotherapeutic agents. This discussion, however, will focus on antimicrobial drug resistance. As antimicrobial drugs become […]

DNA Sequencing: The Backbone of Personalized Medicine

Concept of Personalized Medical Care As a society, we have been accustomed to the concept of a “one-size-fits-all” approach to healthcare. However, this has not been ideal for many people and limits the success of medical management. There are instances where there is some level of tailoring to the individual, but not to the extent […]

How Transposons are Changing the Sequencing Industry

Introduction Mobile DNA segments that can change position, transpose, are transposons (or transposable elements). These “jumping genes” discovered by Barbara McClintock 70 years ago exist in species of all kingdoms, from bacteria to humans. Transposons make up large portions of a species’ genome and have key biological functions. In humans, transposons make up nearly 50% […]

HOW DNA SEQUENCING WORKS

The Basic Structure of DNA We may hear a lot about deoxyribonucleic acid (DNA) and how scientists discover mutations and other information about the specific makeup of DNA; however, how this information is actually obtained may elude many. The process to determine the actual make-up of a strand of DNA is called DNA sequencing. To […]